Feed Lot

SEP-OCT 2018

Feedlots and cow/calf operations in the beef industry who feed 500 or more has annually on grains and concentrates; maintain 500 or more beef cows; backgrounder, stocker/grower, preconditioner; veterinarian, nutritionist, consultant

Issue link: https://feedlotmagazine.epubxp.com/i/1019360

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Page 13 of 47

14 FEED•LOT September/October 2018 predictive of treatment success or failure: Pathogen Load (PL). As the number of bacterial and/ or viral pathogens found in the up- per respiratory tract increased at time of treatment, regardless of an- timicrobial sensitivity pattern, BRD treatment success plummeted. The impact of having two or more pathogens present was significant, and three pathogen combinations, particularly those including Myco- plasma bovis, were associated with poor treatment outcomes. If PL is strongly associated with treatment failure, which of our management practices best addresses it? We can agree that many of our ani- mal health interventions, such as T he primary focus of animal health manage- ment and judicious use of antimicrobials is reducing the number of animals that require treatment. Rightly so. But reducing losses and antimicrobial use also requires improving treatment success in animals needing treatment. And even when the number of animals requiring treatment is modest, losses can be severe when treatment success is low. Many chute-side bovine respira- tory disease (BRD) conversations between cattlemen and veterinar- ians start with, "we need a better drug" and gravitate to discussions on antimicrobial resistance; which is an important topic not only on the minds of people in our industry, but society as a whole. This often results in submitting laboratory work and then a "revolving door" of changing therapy based on culture and sensitivity results with a hope it will improve BRD outcomes. It usually doesn't. Choosing BRD therapy based on antimicrobial susceptibility testing in past treatment failures has been frustrating. Many veterinarians and producers remark that "Product A always looks good on antimicrobial susceptibility testing reports but gives poor results in our treatment programs." Or the reverse, "We frequently get reports back show- ing resistance to Product B, but it performs best in data from our treatment program." When I recently examined a large volume of investigative field work, where pathogen identifica- tion and antimicrobial susceptibil- ity testing was done at the time of BRD treatment, I was unimpressed with the "predictive value" of an- timicrobial susceptibility testing on BRD treatment success. But there was information within these lab results that appeared highly Pathogen load is driver of BRD treatment success ? BY T. ROBIN FALKNER, DVM BRD Treatment Success — Better Drugs or Fewer "Bugs" FEEDLOT FOCUS Biocontainment Is the use of management practices to reduce the movement of pathogens between animals and/or groups

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